Statins: pleiotropic regulators of cardiovascular redox state.

Journal article

Lipid-lowering treatment with statins is one of the most effective therapeutic strategies in cardiovascular medicine because they reduce cardiovascular risk in both primary and secondary prevention. Despite the well-established links between low-density lipoprotein and cardiovascular risk, the clinical benefit from statin treatment is not fully explained by their lipid-lowering potential. A number of pleiotropic effects of statins have been described over the past decade, and their ability to...

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Authors: Antoniades, C; Channon, K

• Publication status: Published
• Journal: Antioxidants and redox signaling
• Volume: 20
• Issue: 8
• Pages: 1195-1197
• Publication date: 2014-03-01
• DOI: 10.1089/ars.2014.5836
• EISSN: 1557-7716
• ISSN: 1523-0864
• Language: English
• Keywords: Cardiovascular System; Oxidative Stress; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Oxidation-Reduction; Cardiovascular Agents; Signal Transduction; Humans