Thesis
HIV-1 induction of macrophage immune mediators
- Abstract:
-
Clinical studies convincingly associate increased monocyte migration and markers of myeloid cell activation with the pathogenesis of inflammatory conditions in HIV-1-infected individuals. However, the mechanisms by which myeloid cells contribute to HIV-1-associated inflammation are poorly understood. HIV-1 infection of human macrophages is believed to induce an innate immune response that includes IFN-I production. Previous studies also implicate the HIV-1 accessory protein Vpr as a potent...
Expand abstract
Actions
Authors
Contributors
+ Sattentau, Q
Department:
University of Oxford
Role:
Supervisor
+ Russell, R
Department:
University of Oxford
Role:
Supervisor
+ James, W
Department:
University of Oxford
Role:
Examiner
+ Noursadeghi, M
Department:
University College London
Role:
Examiner
Funding
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:412497dc-615a-450d-a850-7ca5de303958
- Deposit date:
- 2020-04-23
Terms of use
- Copyright holder:
- Dacon, C
- Copyright date:
- 2019
Metrics
If you are the owner of this record, you can report an update to it here: Report update to this record