Journal article
Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to Type 2 diabetes
- Abstract:
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Background: There is considerable interest in the hypothesis that low frequency, intermediate penetrance variants contribute to the proportion of Type 2 Diabetes (T2D) susceptibility not attributable to the common variants uncovered through genome-wide association approaches. Genes previously implicated in monogenic and multifactorial forms of diabetes are obvious candidates in this respect. In this study, we focussed on exons 8-10 of the HNF1A gene since rare, penetrant mutations in these ex...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 74.4KB)
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(Version of record, doc, 28.0KB)
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- Publisher copy:
- 10.1371/journal.pone.0006615
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Authors
Funding
National Institute for Health Research Oxford Biomedical Research Centre Programme
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Bibliographic Details
- Publisher:
- Public Library of Science Publisher's website
- Journal:
- PLoS ONE Journal website
- Volume:
- 4
- Issue:
- 8
- Article number:
- e6615
- Publication date:
- 2009-08-01
- DOI:
- EISSN:
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1932-6203
Item Description
- Language:
- English
- Subjects:
- UUID:
-
uuid:413a6f03-75c1-4eea-83be-8c5ef09f54ff
- Local pid:
- ora:3094
- Deposit date:
- 2009-11-27
Related Items
Terms of use
- Copyright holder:
- Jafar-Mohammadi et al
- Copyright date:
- 2009
- Notes:
-
Citation: Jafar-Mohammadi, B. et al. (2009). 'Low frequency variants in the exons only encoding isoform A of HNF1A do not contribute to susceptibility to Type 2 diabetes', PLoS ONE, 4(8), e6615. [Available at http://www.plosone.org]. © 2009 Jafar-Mohammadi et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which
permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
- Licence:
- CC Attribution (CC BY)
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