Thesis
Quantitative regulation of inducible genes: comparing models of 'on/off' against continuously variable switches
- Abstract:
-
In order to respond rapidly and appropriately to their environment, cells activate internal signalling pathways, such as the mitogen-activated protein kinase (MAPK) pathways, which elicit appropriate responses through quantitative modulation of gene expression. Conceptually, gene expression may be regulated by a bistable switch or a continuously variable switch. The bistable switch considers the gene in either a stable 'on' state, where transcription happens at a constant rate intrinsic to...
Expand abstract
Actions
Access Document
- Files:
-
-
(pdf, 15.6MB)
-
Why is the content I wish to access not available via ORA?
Bibliographic data (the information relating to research outputs) and full-text items (e.g. articles, theses, reports, etc.) arrive in ORA from several different sources. Unfortunately we are not able to make available the full-text for every research output.
Please contact the ORA team (
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
) if you have queries regarding unavailable content OR if you are aware of a full-text copy we can make available.
Content may be unavailable for the following four reasons
-
Version unsuitable
-
We have not obtained a suitable full-text for a given research output. See this page for more information.
-
Recently completed
-
Sometimes content is held in ORA but is unavailable for a fixed period of time to comply with the policies and wishes of rights holders.
-
Permissions
-
All content made available in ORA should comply with relevant rights, such as copyright. See this page for more information.
-
Clearance
-
Some thesis volumes scanned as part of the digitisation scheme funded by Dr Leonard Polonsky are currently unavailable due to sensitive material or uncleared third-party copyright content. We are attempting to contact authors whose theses are affected.
Alternative access to the full-text
You may be able to access the full-text directly from the publisher's website using the 'Publisher Copy' link in the 'Links & Downloads' box from a research output's ORA record page. This method may require an institutional or individual subscription to the journal/resource.
Funding
Engineering & Physical Sciences Research Council
More from this funder
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:41718e9e-5de9-4187-9cd6-b953469f3fbd
- Deposit date:
- 2016-07-11
Terms of use
- Copyright holder:
- Schneider, C
- Copyright date:
- 2015
If you are the owner of this record, you can report an update to it here: Report update to this record