Journal article
Molecular recognition of the native HIV-1 MPER revealed by STED microscopy of single virions
- Abstract:
-
Antibodies against the Membrane-Proximal External Region (MPER) of the Env gp41 subunit neutralize HIV-1 with exceptional breadth and potency. Due to the lack of knowledge on the MPER native structure and accessibility, different and exclusive models have been proposed for the molecular mechanism of MPER recognition by broadly neutralizing antibodies. Here, accessibility of antibodies to the native Env MPER on single virions has been addressed through STED microscopy. STED imaging of fluoresc...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Springer Nature Publisher's website
- Journal:
- Nature Communications Journal website
- Volume:
- 10
- Article number:
- 78
- Publication date:
- 2019-01-08
- Acceptance date:
- 2018-12-07
- DOI:
- EISSN:
-
2041-1723
- Pmid:
-
30622256
Item Description
- Language:
- English
- Keywords:
- Pubs id:
-
pubs:959166
- UUID:
-
uuid:4199a3f6-b786-496d-a114-de6152840276
- Local pid:
- pubs:959166
- Source identifiers:
-
959166
- Deposit date:
- 2019-07-08
Terms of use
- Copyright holder:
- Carravilla et al
- Copyright date:
- 2019
- Notes:
- © The Author(s) 2019. Open Access. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
- Licence:
- CC Attribution (CC BY)
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