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Journal article

Effects of dopamine depletion on network entropy in the external globus pallidus.

Abstract:

Dopamine depletion in cortical-basal ganglia circuits in Parkinson's disease (PD) grossly disturbs movement and cognition. Classic models relate Parkinsonian dysfunction to changes in firing rates of basal ganglia neurons. However, disturbances in other dynamics of neural activity are also common. Taking both inappropriate firing rates and other dynamics into account and determining how changes in the properties of these neural circuits that occur during PD impact on information coding are th...

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Publication status:
Published

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Publisher copy:
10.1152/jn.00344.2009

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Institution:
University of Oxford
Division:
MPLS
Department:
Engineering Science
Sub department:
Institute of Biomedical Engineering
Role:
Author
Journal:
Journal of neurophysiology
Volume:
102
Issue:
2
Pages:
1092-1102
Publication date:
2009-08-01
DOI:
EISSN:
1522-1598
ISSN:
0022-3077
Source identifiers:
71001
Language:
English
Keywords:
Pubs id:
pubs:71001
UUID:
uuid:41a21224-2bd5-46a1-bb32-1db10cb696d2
Local pid:
pubs:71001
Deposit date:
2012-12-19

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