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The distribution of hypothalamic nitric oxide synthase mRNA in relation to gonadotrophin-releasing hormone neurons.

Abstract:

Using probes for rat neural nitric oxide synthase (NOS) mRNA and GnRH mRNA, we performed in situ hybridization to survey NOS mRNA distribution within the hypothalamus of the male and female rat and sought evidence for its expression in GnRH neurons. The NOS cRNA probe was radiolabelled with 35S, and a digoxigenin-labeled rat GnRH cRNA probe was used for double-label studies. NOS mRNA was localized in discrete hypothalamic areas, in grain clusters suggestive of individual neurons. NOS mRNA-pos...

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Publication status:
Published

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Publisher copy:
10.1677/joe.0.140r005

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
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Journal:
Journal of endocrinology
Volume:
140
Issue:
2
Pages:
R5-R8
Publication date:
1994-02-01
DOI:
EISSN:
1479-6805
ISSN:
0022-0795
Source identifiers:
138430
Language:
English
Keywords:
Pubs id:
pubs:138430
UUID:
uuid:422e67a4-00ab-4529-b8c9-6620958646e1
Local pid:
pubs:138430
Deposit date:
2012-12-19

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