Conference item
A new role for RGS-1 in vascular function and blood pressure regulation
- Abstract:
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The Regulator of G-Protein Signalling-1 (RGS1) controls G protein coupled receptor signalling by acting as a GTPase-activating protein for heterotrimeric G proteins. RGS1 has contrasting roles in haematopoietic and non-haematopoietic cells. We have previously shown that Rgs1 regulates macrophage accumulation in Angiotensin II (Ang II)-induced aortic aneurysms and Rgs1-/-ApoE-/- mice are protected from Ang II-induced aortic aneurysm rupture compared to ApoE-/- mice. Conversely, Ang II treatmen...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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- Publisher copy:
- 10.1093/cvr/cvy060.254
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Frontiers in CardioVascular Biology 2018 Journal website
- Host title:
- Frontiers in CardioVascular Biology 2018
- Publication date:
- 2018-04-23
- DOI:
- Source identifiers:
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846772
Item Description
- Pubs id:
-
pubs:846772
- UUID:
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uuid:42304be4-898c-4036-8793-d3215022f81c
- Local pid:
- pubs:846772
- Deposit date:
- 2018-07-24
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- Copyright date:
- 2018
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