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Journal article

Perivascular adipose tissue as a regulator of vascular disease pathogenesis: identifying novel therapeutic targets.

Abstract:

Adipose tissue (AT) is an active endocrine organ with the ability to dynamically secrete a wide range of adipocytokines. Importantly, its secretory profile is altered in various cardiovascular disease states. AT surrounding vessels, or perivascular AT (PVAT), is recognized in particular as an important local regulator of vascular function and dysfunction. Specifically, PVAT has the ability to sense vascular paracrine signals and respond by secreting a variety of vasoactive adipocytokines. Due...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/bph.13666

Authors


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Institution:
University of Oxford
Oxford college:
Trinity College
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
National Institute for Health Research More from this funder
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Grant:
ITN network RADOX-GA-316738
Publisher:
Wiley Publisher's website
Journal:
British Journal of Pharmacology Journal website
Volume:
174
Issue:
20
Pages:
3411–3424
Publication date:
2016-11-07
Acceptance date:
2016-10-28
DOI:
EISSN:
1476-5381
ISSN:
0007-1188
Source identifiers:
666532
Language:
English
Keywords:
Pubs id:
pubs:666532
UUID:
uuid:42985c70-31f6-45dd-9088-3256b8aae0ec
Local pid:
pubs:666532
Deposit date:
2016-12-22

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