Journal article
The importance of early immunotherapy in 103 patients with faciobrachial dystonic seizures
- Abstract:
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Faciobrachial dystonic seizures (FBDS) and limbic encephalitis closely associate with LGI1- antibodies. Here, we describe 103 consecutive patients with FBDS and LGI1-antibodies to understand clinical, therapeutic and serological differences between those with and without cognitive impairment (CI), and to determine whether cessation of FBDS can prevent CI. The 22/103 patients without CI typically had normal brain imaging, EEGs, sodium levels (p<0·0001) and almost exclusive IgG4 LGI1-antibod...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(pdf, 979.6KB)
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- Publisher copy:
- 10.1093/brain/awx323
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Authors
Funding
Wellcome Trust
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Epilepsy Research UK
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BMA Research Grant
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Fulbright UK-US Commission
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Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Brain Journal website
- Volume:
- 141
- Issue:
- 2
- Pages:
- 348–356
- Publication date:
- 2017-12-18
- Acceptance date:
- 2017-10-17
- DOI:
- EISSN:
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1460-2156
- ISSN:
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0006-8950
Item Description
- Keywords:
- Pubs id:
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pubs:743441
- UUID:
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uuid:42990a4e-23be-4e55-aa8a-12f8321742dd
- Local pid:
- pubs:743441
- Deposit date:
- 2017-11-04
Terms of use
- Copyright holder:
- Thompson et al
- Copyright date:
- 2017
- Notes:
- © The Author (2017). Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
- Licence:
- CC Attribution (CC BY)
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