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Journal article

CASPR2 autoantibodies are raised during pregnancy in mothers of children with mental retardation and disorders of psychological development but not autism

Abstract:

BACKGROUND, METHODS AND OBJECTIVES: Maternal autoantibodies to neuronal proteins may be one cause of neurodevelopmental disorders. This exploratory study used the Danish archived midgestational sera and their nationwide registers to search for antibodies to the N-methyl-D-aspartate receptor (NMDAR) and contactin-associated protein-like 2 (CASPR2) in maternal sera, and to relate them to subsequent psychiatric diagnoses in the woman or her child. RESULTS: In a sample of 192 women, there was no ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1136/jnnp-2016-315251

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Role:
Author
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Funding agency for:
Coutinho, E
Grant:
Programme for Advanced Medical Education
Stanley Medical Research Institute More from this funder
Publisher:
BMJ Publishing Group Publisher's website
Journal:
Journal of Neurology, Neurosurgery and Psychiatry Journal website
Volume:
88
Issue:
9
Pages:
718-721
Publication date:
2017-06-01
Acceptance date:
2017-03-24
DOI:
EISSN:
1468-330X
ISSN:
0022-3050
Source identifiers:
698686
Language:
English
Keywords:
Pubs id:
pubs:698686
UUID:
uuid:42e01598-79dd-475f-8a0f-6a4f674c478c
Local pid:
pubs:698686
Deposit date:
2017-08-09

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