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The bacterial sequential Markov coalescent

Abstract:

Bacteria can exchange and acquire new genetic material from other organisms directly and via the environment. This process, known as bacterial recombination, has a strong impact on the evolution of bacteria, for example leading to the spread of antibiotic resistance across clades and species, and to the avoidance of clonal interference. Recombination hinders phylogenetic and transmission inference because it creates patterns of substitutions (homoplasies) inconsistent with the hypothesis of a...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1534/genetics.116.198796

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Institution:
University of Oxford
Oxford college:
St John's College
Role:
Author
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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
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Funding agency for:
De Maio, N
Grant:
James Martin Research Fellowship
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Funding agency for:
Wilson, D
Grant:
101237/Z/13/Z
More from this funder
Funding agency for:
Wilson, D
Grant:
101237/Z/13/Z
Publisher:
Genetics Society of America Publisher's website
Journal:
Genetics Journal website
Volume:
206
Issue:
1
Pages:
333-343
Publication date:
2017-05-05
Acceptance date:
2017-02-14
DOI:
EISSN:
1943-2631
ISSN:
0016-6731
Keywords:
Pubs id:
pubs:680564
UUID:
uuid:430ecade-0486-42cb-bb19-4a1821b12ad7
Local pid:
pubs:680564
Deposit date:
2017-02-16

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