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Thesis

Investigations of the potential schizophrenia susceptibility gene Kinase Interacting with Stathmin (KIS)

Abstract:

Single nucleotide polymorphisms (SNPs) within the gene encoding the serine threonine kinase KIS (Kinase Interacting with Stathmin, also known as UHMK1) have recently been associated with schizophrenia. However, little is known about the neurobiology of KIS or the mechanisms through which disease-associated SNPs may increase susceptibility to schizophrenia. The studies presented in this thesis focus on the distribution of KIS and its mRNA, address the mechanisms through which KIS may confer...

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Institution:
University of Oxford
Division:
MSD
Department:
Psychiatry
Research group:
Molecular Neuropathology Group
Oxford college:
Wolfson College
Role:
Author

Contributors

Role:
Supervisor
Role:
Supervisor
Publication date:
2010
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:432fc195-815c-4bc6-945f-c2b59aa3538c
Local pid:
ora:5499
Deposit date:
2011-06-24

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