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Journal article

Targeting TGFβ signalling in cancer: Toward context-specific strategies

Abstract:
The transforming growth factor beta (TGFβ) signalling pathway regulates a range of important cellular processes in a context-dependent manner. Recent discoveries have provided important insights into the regulation of the TGFβ pathway and its change from an antitumorigenic to a protumorigenic pathway. These findings may have important implications for cancer stem cell (CSC) functions and therapeutic strategies.
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.trecan.2020.03.010

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Role:
Author
Publisher:
Elsevier Publisher's website
Journal:
Trends in Cancer Journal website
Volume:
6
Issue:
7
Pages:
538-540
Publication date:
2020-04-08
Acceptance date:
2020-03-23
DOI:
EISSN:
2405-8033
ISSN:
2405-8033
Language:
English
Keywords:
Pubs id:
1096177
Local pid:
pubs:1096177
Deposit date:
2020-03-24

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