Journal article
Stakeholder views on secondary findings in whole-genome and whole-exome sequencing: a systematic review of quantitative and qualitative studies
- Abstract:
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Purpose: As whole-exome and whole-genome sequencing (WES/WGS) move into routine clinical practice, it is timely to review data that might inform the debate around secondary findings (SF) and the development of policies that maximize participant benefit.
Methods: We systematically searched for qualitative and quantitative studies that explored stakeholder views on SF in WES/WGS. Framework analysis was undertaken to identify major themes.
Results: 44 articles report...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.8MB)
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- Publisher copy:
- 10.1038/gim.2016.109
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Authors
Funding
+ National Institute for Health Research Biomedical Research Centre
More from this funder
Funding agency for:
Ormondroyd, E
+ National Institute for Health Research School for Primary Care Research
More from this funder
Funding agency for:
Fletcher, B
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- Genetics in Medicine Journal website
- Publication date:
- 2016-09-01
- Acceptance date:
- 2016-06-20
- DOI:
- EISSN:
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1530-0366
- ISSN:
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1098-3600
- Source identifiers:
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641147
Item Description
- Keywords:
- Pubs id:
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pubs:641147
- UUID:
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uuid:435bc69e-6edf-471c-80b7-0594e54df75a
- Local pid:
- pubs:641147
- Deposit date:
- 2016-09-01
Terms of use
- Copyright holder:
- Mackley, et al
- Copyright date:
- 2016
- Notes:
- This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
- Licence:
- CC Attribution (CC BY)
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