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The expression of Neuroserpin and its role in neonatal hypoxic-ischaemic encephalopathy

Abstract:

Background: Perinatal hypoxic ischaemia is one of the most prevalent causes of neonatal morbidity and mortality worldwide. Hypothermia is currently the only available treatment option. Neuroserpin, an inhibitor of tissue plasminogen activator and an endogenously secreted protein, has been shown to result in a reduction in brain damage and overall functional improvements in models of adult cerebral infarction (Millar et al., 2017). It has therefore been hypothesised that it may a...

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Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

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Supervisor
Medical Research Council More from this funder
Type of award:
MSc by Research
Level of award:
Masters
Awarding institution:
University of Oxford
Language:
English
UUID:
uuid:43769069-9977-4488-917b-be57439dccb2
Deposit date:
2019-07-10

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