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IFITM3: how genetics influence influenza infection demographically

Abstract:

The role of host genetics in influenza infection is unclear despite decades of interest. Confounding factors such as age, sex, ethnicity and environmental factors have made it difficult to assess the role of genetics without influence. In recent years a single nucleotide polymorphism, interferon-induced transmembrane protein 3 (IFITM3) rs12252, has been shown to alter the severity of influenza infection in Asian populations. In this review we investigate this polymorphism as well as several o...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1016/j.bj.2019.01.004

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Department:
CF RDM - INVESTIGATIVE MEDICINE DIVISION
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM
Sub department:
RDM - Investigative Medicine Division
Role:
Author
More from this funder
Grant:
MR/P021336/1 Crick code 10590
John Fell Fund More from this funder
Publisher:
Elsevier Publisher's website
Journal:
Biomedical Journal
Volume:
42
Issue:
1
Pages:
19-26
Publication date:
2019-03-20
Acceptance date:
2019-01-07
DOI:
EISSN:
2320-2890
ISSN:
2319-4170
Keywords:
Pubs id:
pubs:983383
UUID:
uuid:43b0626a-057a-4e61-bb68-103415e057e6
Local pid:
pubs:983383
Deposit date:
2019-03-21

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