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Journal article

Chylomicron-derived fatty acid spillover in adipose tissue: a signature of metabolic health?

Abstract:
Context and objectives: Spillover of fatty acids (FAs) into the plasma nonesterified fatty acid (NEFA) pool, because of an inability of adipose tissue (AT) to accommodate sufficient fat uptake, has been suggested to contribute to obesity-related insulin resistance. Using specific labeling techniques, we compared the proportion of spillover-derived NEFA across a range of adiposity. Participants and methods: Seventy-one healthy men and women were fed a mixed... Expand abstract
Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1210/jc.2017-01517

Authors


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Institution:
University of Oxford
Division:
Churchill Hospital
Department:
Endocrinology and Metabolism; Oxford Centre for Diabetes
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Churchill Hospital
Department:
Endocrinology and Metabolism; Oxford Centre for Diabetes
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
RDM; OCDEM
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
National Institute for Health Research More from this funder
Fonds de Recherche du Québec-Santé More from this funder
Heart and Lung Institute Foundation More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Journal of Clinical Endocrinology and Metabolism Journal website
Volume:
103
Issue:
1
Pages:
25–34
Publication date:
2017-11-01
Acceptance date:
2017-10-27
DOI:
EISSN:
1945-7197
ISSN:
0021-972X
Source identifiers:
742307
Keywords:
Pubs id:
pubs:742307
UUID:
uuid:43fd32ee-6a2d-4638-8ef4-d7e3df848069
Local pid:
pubs:742307
Deposit date:
2017-11-02

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