Thesis
Computational studies of transmembrane helix insertion and association
- Abstract:
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Membrane proteins perform a variety of functions essential for the viability of the cell, including transport and signalling across the membrane. Most membrane proteins are formed from bundles of transmembrane helices. In this thesis molecular dynamics simulations have been used to investigate helix insertion into bilayers and helix association within bilayers. The potentials of mean force for the insertion of helices derived from the cystic fibrosis transmembrane conductance regulator in...
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Funding
Bibliographic Details
- Publication date:
- 2011
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- Oxford University, UK
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:440da098-5bd6-4fcb-8396-645517ac2122
- Local pid:
- ora:8174
- Deposit date:
- 2014-03-10
Terms of use
- Copyright holder:
- Chetwynd, A
- Copyright date:
- 2012
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