Thesis icon

Thesis

Computational studies of transmembrane helix insertion and association

Abstract:

Membrane proteins perform a variety of functions essential for the viability of the cell, including transport and signalling across the membrane. Most membrane proteins are formed from bundles of transmembrane helices. In this thesis molecular dynamics simulations have been used to investigate helix insertion into bilayers and helix association within bilayers. The potentials of mean force for the insertion of helices derived from the cystic fibrosis transmembrane conductance regulator in...

Expand abstract

Actions


Access Document


Files:

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Research group:
Structural Bioinformatics and Computational Biochemistry Unit
Oxford college:
Keble College
Role:
Author

Contributors

Division:
MSD
Department:
Biochemistry
Role:
Supervisor
More from this funder
Funding agency for:
Chetwynd, A
Publication date:
2011
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
Language:
English
Keywords:
Subjects:
UUID:
uuid:440da098-5bd6-4fcb-8396-645517ac2122
Local pid:
ora:8174
Deposit date:
2014-03-10

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP