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Prediction of serotypes causing invasive pneumococcal disease in unvaccinated and vaccinated populations.

Abstract:

INTRODUCTION: Before the introduction of the heptavalent pneumococcal conjugate vaccine (Prevnar-7), the relative prevalence of serotypes of Streptococcus pneumoniae was fairly stable worldwide. We sought to develop a statistical tool to predict the relative frequency of different serotypes among disease isolates in the pre- and post-Prevnar-7 eras using the limited amount of data that is widely available. METHODS: We initially used pre-Prevnar-7 carriage prevalence and estimates of invasiven...

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
Journal:
Epidemiology (Cambridge, Mass.)
Volume:
22
Issue:
2
Pages:
199-207
Publication date:
2011-03-01
DOI:
EISSN:
1531-5487
ISSN:
1044-3983
Source identifiers:
246741
Language:
English
Keywords:
Pubs id:
pubs:246741
UUID:
uuid:4495c08c-6af6-4e5e-b0ed-be9bc64e4d2d
Local pid:
pubs:246741
Deposit date:
2012-12-19

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