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Thirty-five common variants for coronary artery disease: the fruits of much collaborative labour.

Abstract:

Coronary artery disease (CAD) is the leading cause of death worldwide. Affected individuals cluster in families in patterns that reflect the sharing of numerous susceptibility genes. Genome-wide and large-scale gene-centric genotyping studies that involve tens of thousands of cases and controls have now mapped common disease variants to 34 distinct loci. Some coronary disease common variants show allelic heterogeneity or copy number variation. Some of the loci include candidate genes that imp...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1093/hmg/ddr384

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Human Genetics Wt Centre
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
RDM Cardiovascular Medicine
Role:
Author
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Grant:
LSHM-CT-2007-037273
British Heart Foundation More from this funder
Publisher:
Oxford University Press Publisher's website
Journal:
Human molecular genetics Journal website
Volume:
20
Issue:
R2
Pages:
R198-R205
Publication date:
2011-10-01
DOI:
EISSN:
1460-2083
ISSN:
0964-6906
Source identifiers:
172123
Language:
English
Keywords:
UUID:
uuid:4580959c-3aad-426f-9ed3-19ad60dbfdde
Local pid:
pubs:172123
Deposit date:
2012-12-19

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