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Coalescence in a random background

Abstract:

We consider a single genetic locus which carries two alleles, labelled P and Q. This locus experiences selection and mutation. It is linked to a second neutral locus with recombination rate r. If r = 0, this reduces to the study of a single selected locus. Assuming a Moran model for the population dynamics, we pass to a diffusion approximation and, assuming that the allele frequencies at the selected locus have reached stationarity, establish the joint generating function for the genealogy of...

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Publication status:
Published

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Publisher copy:
10.1214/105051604000000099

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Institution:
University of Oxford
Division:
MPLS
Department:
Statistics
Role:
Author
Journal:
ANNALS OF APPLIED PROBABILITY
Volume:
14
Issue:
2
Pages:
754-785
Publication date:
2004-05-01
DOI:
EISSN:
1050-5164
ISSN:
1050-5164
Source identifiers:
97457
Language:
English
Keywords:
Pubs id:
pubs:97457
UUID:
uuid:464d46b5-57f0-40c6-a0e1-d80162cb3087
Local pid:
pubs:97457
Deposit date:
2012-12-19

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