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Use of iminosugar derivatives to inhibit ion channel activity

Alternative title:
World Intellectual Property Ogranization patent WO/2004/047719
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
World Intellectual Property Ogranization Publisher's website
Publication date:
2004-06-10
Patent status:
Issued/granted
Patent number:
WO2004047719
Application number:
PCT/IB2003/006471
Source identifiers:
383431
Documentation:
Disclosed are methods and kits to treat HCV infection by administering an iminosugar derivative compound that is effective to inhibit the activity of HCV p7 protein, and methods by which to screen for compounds that inhibit the activity of p7 protein or variants thereof. The disclosed N-substituted imino compounds, and pharmaceutical compositions thereof, inhibit the capability of HCV p7 to permeabilize membranes. Particularly efficacious compounds are imino sugars derived from N-alkylated pi... Expand documentation
Pubs id:
pubs:383431
UUID:
uuid:46909b18-f58f-4e1f-8025-042725e482eb
Local pid:
pubs:383431
Deposit date:
2016-02-11

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