Thesis
Unbiased molecular definition of epithelial barrier formation and defects driving inflammatory bowel disease
- Abstract:
-
The intestinal epithelial barrier is one of the body’s largest mucosal surfaces. The cells involved reflect the numerous functions the epithelium must perform. The barrier requires time critical co-ordination with other intestinal cell compartments in utero for normal development. In maturity, dysregulation of the barrier or cross-talk can lead to disease such as inflammatory bowel disease (IBD).
Despite the importance of the intestinal epithelium in development and health, charact...
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Authors
Contributors
+ Simmons, A
Role:
Supervisor
ORCID:
0000-0003-3454-0710
+ Johnson, P
Role:
Supervisor
+ Leedham, S
Role:
Examiner
+ Di Coppi, P
Role:
Examiner
Funding
+ Wellcome Trust
More from this funder
Funder identifier:
http://dx.doi.org/10.13039/100010269
Funding agency for:
Simmons, A
Fawkner-Corbett, D
Grant:
102176/B/13/Z
+ Royal College of Surgeons of England
More from this funder
Funding agency for:
Fawkner-Corbett, D
Grant:
British Association of Paediatric Surgeons Research Fellowship
Oxford Health Services Research Committee
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- Deposit date:
- 2022-01-27
Related Items
Terms of use
- Copyright holder:
- Fawkner-Corbett, D
- Copyright date:
- 2021
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