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Thesis

Investigation of the tumour vascular response to single and fractionated irradiation

Alternative title:
The effect of radiation therapy on tumour vasculature
Abstract:

The effect of radiation therapy on tumour vasculature has been a subject of debate over the years. Increased oxygenation and perfusion have been documented during radiation treatments. Conversely, death of irradiated tumour endothelial cells by apoptosis, predicted to impair blood flow, has been proposed as a major determinant of tumour control. To approach these contradictions, we used video 2-photon microscopy to study the vascular response to irradiation in two different murine tumour m...

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Division:
MSD
Department:
Oncology
Role:
Author

Contributors

Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Supervisor
Cancer Research UK More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:46b9fc81-e195-4f44-a9b4-612bcd0b53a9
Deposit date:
2020-04-17

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