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Journal article

Effects of native, triglyceride-enriched, and oxidatively modified LDL on plasminogen activator inhibitor-1 expression in human endothelial cells.

Abstract:

Whereas VLDL has consistently been shown to induce a concentration-dependent increase in the expression of plasminogen activator inhibitor-1 (PAI-1) in human umbilical vein endothelial cells (HUVECs) and liver cells, variable effects have been reported for native and oxidatively modified LDL. In the present study, activation of PAI-1 protein and mRNA expression by native LDL (nLDL), UV-oxidized LDL (uvLDL), and triglyceride (TG)-enriched LDL was studied in HUVECs by using different incubation...

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Publication status:
Published

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Publisher copy:
10.1161/01.atv.19.5.1354

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Institution:
University of Oxford
Division:
MSD
Department:
RDM
Sub department:
OCDEM
Role:
Author
Journal:
Arteriosclerosis, thrombosis, and vascular biology
Volume:
19
Issue:
5
Pages:
1354-1360
Publication date:
1999-05-01
DOI:
EISSN:
1524-4636
ISSN:
1079-5642
Source identifiers:
8912
Language:
English
Keywords:
Pubs id:
pubs:8912
UUID:
uuid:46c31cb7-2881-40b1-8b3c-9303b905651f
Local pid:
pubs:8912
Deposit date:
2012-12-19

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