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Thesis

Profiling Doublesex-DNA interactions with targeted DamID in Drosophila melanogaster

Abstract:

The transcriptional regulators doublesex (dsx) and fruitless (fru) function together to specify sexual physiology and behaviour in Drosophila melanogaster. Whilst fru has only been located in insect lineages, dsx is structurally and functionally conserved throughout the animal kingdom. The role of FRU proteins as transcriptional regulators has been studied extensively with DamID – a method that uses DNA adenine methylation to create ‘fingerprints’ in the genome ...

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Author

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Institution:
University of Oxford
Division:
MSD
Department:
Physiology Anatomy & Genetics
Role:
Supervisor
Medical Research Council More from this funder
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
UUID:
uuid:47295b56-725e-422d-a3b9-fb78fc33c7a9
Deposit date:
2020-03-02

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