Journal article
Similar active genes cluster in specialized transcription factories
- Abstract:
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How transcription affects the way specific genes are arranged within the nucleus remains to be fully understood. We examine here whether transcription occurs in discrete sites (factories) containing the required machinery and whether these sites specialize in transcribing different genes. We cotransfected plasmids encoding a common origin of replication but different transcription units into cells, where they are assembled into minichromosomes that the cellular machinery replicates and transc...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.6MB)
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(Version of record, pdf, 153.3KB)
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- Publisher copy:
- 10.1083/jcb.200710053
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Authors
Bibliographic Details
- Publisher:
- Rockefeller University Press Publisher's website
- Journal:
- Journal of Cell Biology Journal website
- Volume:
- 181
- Issue:
- 4
- Pages:
- 615-623
- Publication date:
- 2008-05-01
- DOI:
- EISSN:
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1540-8140
- ISSN:
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0021-9525
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:47404948-0d95-47a8-aaa7-55c128f75095
- Local pid:
- ora:4093
- Deposit date:
- 2010-08-23
Related Items
Terms of use
- Copyright holder:
- Xu and Cook
- Copyright date:
- 2008
- Notes:
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Citation: Xu, M. & Cook, P. R. (2008). 'Similar active genes cluster in specialized transcription factories'. Originally published in the Journal of Cell Biology 181(4), 615-623. DOI: 10.1083/jcb.200710053. This is an open-access article distributed under the terms of the Creative Commons
Attribution-Noncommercial-Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/ and http://creativecommons.org/licenses/by-nc-sa/3.0/legalcode. You may not use this article for commercial purposes, but you may use, distribe, and reproduce the article in any medium, provided the original author and source are credited. If you alter, transform, or build upon this work, you may distribute the resulting work only under the same or similar license to this one.
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