Radiolabelled copper complexes for cancer imaging
Chapter One introduces molecular imaging and the modalities available for oncological imaging. The radioisotopes and imaging agents for Positron Emission Tomography (PET) and Single Photon Emission Computed Tomography (SPECT) are discussed together with the bifunctional chelator approach for radiolabelling of biomolecules. Finally, the chemistry and radioisotopes of copper are described, and copper bis(thiosemicarbazonato) complexes introduced in the context of PET imaging.
(Dissemination version, pdf, 9.7MB)
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- University of Oxford
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- Hueting, R
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