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Clinical diagnosis of hepatic fibrosis using human serum APOL1 as biomarker

Alternative title:
European Patent Office patent EP2469283 (A1)
Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Biochemistry
Role:
Author
Publisher:
European Patent Office Publisher's website
Publication date:
2012-06-27
Patent status:
Issued/granted
Patent number:
EP2469283
Application number:
11174936
Source identifiers:
383417
Documentation:
The inventors have proposed a novel panel of human serum protein biomarkers for diagnosing hepatic fibrosis and cirrhosis. Presently there is no reliable non-invasive way of assessing liver fibrosis. A 2D-PAGE based proteomics study was used to identify potential fibrosis biomarkers. Serum from patients with varying degrees of hepatic scarring induced by infection with the hepatitis C virus (HCV) was analysed. Several proteins associated with liver scarring and/or viral infection were identif... Expand documentation
Pubs id:
pubs:383417
UUID:
uuid:477936a8-6b33-4ecf-8826-49e10a8c8082
Local pid:
pubs:383417
Deposit date:
2016-02-04

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