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Journal article

Escape of human immunodeficiency virus from immune control.

Abstract:

Cytotoxic T lymphocytes (CTL) play a crucial role in the attempt to control infection with human immunodeficiency virus (HIV). Variation in epitopes recognized by CTL is common and frequently offers potential escape routes for mutant virus. Proof of escape, however, requires demonstration of increased frequency of virus particles or provirus that carry the escape sequence. There are now several recorded examples of virus variants that escape from CTL and are then selected. Most dramatic are t...

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Publication status:
Published

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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
NDM Experimental Medicine
Role:
Author
Journal:
Annual review of immunology
Volume:
15
Issue:
1
Pages:
271-296
Publication date:
1997-01-01
DOI:
EISSN:
1545-3278
ISSN:
0732-0582
Source identifiers:
25560
Language:
English
Keywords:
Pubs id:
pubs:25560
UUID:
uuid:479584af-0c46-4d7b-b746-639b0c1445f8
Local pid:
pubs:25560
Deposit date:
2012-12-19

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