Journal article
Separating speed and ability to displace roadblocks during DNA translocation by FtsK
- Abstract:
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FtsK translocates dsDNA directionally at > 5 kb/s, even under strong forces. In vivo, the action of FtsK at the bacterial division septum is required to complete the final stages of chromosome unlinking and segregation. Despite the availability of translocase structures, the mechanism by which ATP hydrolysis is coupled to DNA translocation is not understood. Here, we use covalently linked translocase subunits to gain insight into the DNA translocation mechanism. Covalent trimers o...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 1.2MB)
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(Version of record, pdf, 1.2MB)
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- Publisher copy:
- 10.1038/emboj.2010.29
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Funding
+ Biotechnology and Biological Sciences Research Council
More from this funder
Funding agency for:
Chivers, C
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Bibliographic Details
- Publisher:
- Nature Publishing Group Publisher's website
- Journal:
- EMBO Journal Journal website
- Volume:
- 29
- Issue:
- 8
- Pages:
- 1423-1433
- Publication date:
- 2010-04-08
- DOI:
- EISSN:
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1460-2075
- ISSN:
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0261-4189
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
-
uuid:47c692f7-24b5-41b0-ad7c-85460bc2aeea
- Local pid:
- ora:3778
- Deposit date:
- 2010-05-14
Related Items
Terms of use
- Copyright holder:
- E Crozat et al
- Copyright date:
- 2010
- Notes:
-
Copyright © 2010 European Molecular Biology Organization. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits
distribution, and reproduction in anymedium, provided the original author and source are credited. This license does not
permit commercial exploitation without specific permission Citation: Crozat, E. et al. (2010). 'Separating speed and ability to displace roadblocks during DNA translocation by FtsK', EMBO Journal 29(8), 1423-1433.
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