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Journal article

Treatment response in enteric fever in an era of increasing antimicrobial resistance: an individual patient data analysis of 2092 participants enrolled into 4 randomized, controlled trials in Nepal

Abstract:

Background: Enteric fever, caused by Salmonella Typhi and Salmonella Paratyphi A, is the leading cause of bacterial febrile disease in South Asia.

Methods: Individual data from 2092 patients with enteric fever randomized into 4 trials in Kathmandu, Nepal, were pooled. All trials compared gatifloxacin with 1 of the following comparator drugs: cefixime, chloramphenicol, ofloxacin, or ceftriaxone. Treatment outcomes were evaluated according to antimicrobial if S. Typhi/Paratyphi ...

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Publication status:
Published
Peer review status:
Peer reviewed

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Files:
Publisher copy:
10.1093/cid/cix185

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
NDM
Sub department:
Tropical Medicine
Role:
Author
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More from this funder
Funding agency for:
Baker, S
Grant:
100087/Z/12/Z
More from this funder
Funding agency for:
Baker, S
Grant:
100087/Z/12/Z
Publisher:
Oxford University Press Publisher's website
Journal:
Clinical Infectious Diseases Journal website
Volume:
64
Issue:
11
Pages:
522–1531
Publication date:
2017-02-28
Acceptance date:
2017-02-25
DOI:
EISSN:
1537-6591
ISSN:
1058-4838
Source identifiers:
686792
Language:
English
Keywords:
Pubs id:
pubs:686792
UUID:
uuid:4801d9d0-a41d-499d-9928-cf14fdb24301
Local pid:
pubs:686792
Deposit date:
2017-03-31

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