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Dopamine regulates the impact of the cerebral cortex on the subthalamic nucleus-globus pallidus network.

Abstract:

The subthalamic nucleus-globus pallidus network plays a central role in basal ganglia function and dysfunction. To determine whether the relationship between activity in this network and the principal afferent of the basal ganglia, the cortex, is altered in a model of Parkinson's disease, we recorded unit activity in the subthalamic nucleus-globus pallidus network together with cortical electroencephalogram in control and 6-hydroxydopamine-lesioned rats under urethane anaesthesia. Subthalamic...

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Institution:
University of Oxford
Division:
MSD
Department:
Pharmacology
Role:
Author
Journal:
Neuroscience
Volume:
106
Issue:
2
Pages:
313-330
Publication date:
2001-01-01
DOI:
EISSN:
1873-7544
ISSN:
0306-4522
Source identifiers:
330504

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