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Evaluation of the efficacy and safety of intravenous remdesivir in adult patients with severe COVID-19: study protocol for a phase 3 randomized, double-blind, placebo-controlled, multicentre trial

Abstract:

Background Coronavirus disease 2019 (COVID-19), caused by a novel corinavirus (later named SARS-CoV-2 virus), was fistly reported in Wuhan, Hubei Province, China towards the end of 2019. Large-scale spread within China and internationally led the World Health Organization to declare a Public Health Emergency of International Concern on 30th January 2020. The clinical manifestations of COVID-19 virus infection include asymptomatic infection, mild upper respiratory symptoms, severe viral pneumo...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13063-020-04352-9

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
NDM
Role:
Author
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Publisher:
BioMed Central Publisher's website
Journal:
Trials Journal website
Volume:
21
Issue:
1
Article number:
422
Publication date:
2020-05-24
Acceptance date:
2020-04-27
DOI:
EISSN:
1745-6215
ISSN:
1745-6215
Pmid:
32448345
Language:
English
Keywords:
Pubs id:
1106709
Local pid:
pubs:1106709
Deposit date:
2020-06-12

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