Journal article icon

Journal article

Expanding the diversity of chemical protein modification allows post-translational mimicry.

Abstract:

One of the most important current scientific paradoxes is the economy with which nature uses genes. In all higher animals studied, we have found many fewer genes than we would have previously expected. The functional outputs of the eventual products of genes seem to be far more complex than the more restricted blueprint. In higher organisms, the functions of many proteins are modulated by post-translational modifications (PTMs). These alterations of amino-acid side chains lead to higher struc...

Expand abstract
Publication status:
Published

Actions


Access Document


Publisher copy:
10.1038/nature05757

Authors


More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Role:
Author
Expand authors...
Journal:
Nature
Volume:
446
Issue:
7139
Pages:
1105-1109
Publication date:
2007-04-01
DOI:
EISSN:
1476-4687
ISSN:
0028-0836
Source identifiers:
33832
Language:
English
Keywords:
Pubs id:
pubs:33832
UUID:
uuid:48dbf33e-a26e-4928-9166-12053475848b
Local pid:
pubs:33832
Deposit date:
2012-12-19

Terms of use


Views and Downloads






If you are the owner of this record, you can report an update to it here: Report update to this record

TO TOP