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Functional segmentation of the anterior limb of the internal capsule: Linking white matter abnormalities to specific connections

Abstract:

The anterior limb of the internal capsule (ALIC) carries thalamic and brainstem fibers from prefrontal cortical regions that are associated with different aspects of emotion, motivation, cognition processing, and decision-making. This large fiber bundle is abnormal in several psychiatric illnesses and a major target for deep brain stimulation. Yet, we have very little information about where specific prefrontal fibers travel within the bundle. Using a combination of tracing studies and diffus...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1523/JNEUROSCI.2335-17.2017

Authors


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Role:
Author
ORCID:
0000-0003-2868-3934
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Role:
Author
ORCID:
0000-0003-4349-1201
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Institution:
University of Oxford
Division:
MSD
Department:
Clinical Neurosciences
Oxford college:
Linacre College
Role:
Author
ORCID:
0000-0003-3234-5639
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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Clinical Neurosciences
Role:
Author
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Role:
Author
ORCID:
0000-0003-0893-5364
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Publisher:
Society for Neuroscience Publisher's website
Journal:
Journal of Neuroscience Journal website
Volume:
38
Issue:
8
Pages:
2106-2117
Publication date:
2018-02-21
Acceptance date:
2017-12-18
DOI:
EISSN:
1529-2401
ISSN:
0270-6474
Pmid:
29358360
Source identifiers:
821344
Language:
English
Keywords:
Pubs id:
pubs:821344
UUID:
uuid:48e90b0d-8932-4481-964c-672293937948
Local pid:
pubs:821344
Deposit date:
2018-10-15

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