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Journal article

Optimizing parallel induction of HIV type 1-specific antibody and T-cell responses by multicomponent subunit vaccines.

Abstract:

OBJECTIVES:: Protection against HIV type 1 (HIV-1) infection/AIDS will likely require concerted actions of protective CD8 killer T cells and protective antibodies. The challenges in inducing such effectors by active immunization are such that the T-cell and antibody vaccine components require separate development. Here, a rational attempt is taken to combine two separately optimized heterologous regimens into a single T-cell-inducing and antibody-inducing vaccination schedule with minimal ind...

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Publication status:
Published

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Publisher:
Lippincott Williams and Wilkins
Journal:
AIDS (London, England)
Volume:
28
Issue:
17
Pages:
2495-2504
Publication date:
2014-09-01
DOI:
EISSN:
1473-5571
ISSN:
0269-9370
Source identifiers:
485051
Language:
English
Keywords:
Pubs id:
pubs:485051
UUID:
uuid:48ef10f9-fc31-4185-9f6f-d69c9b2a9c3c
Local pid:
pubs:485051
Deposit date:
2014-09-26

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