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Elucidating the role of chromatin state and transcription factors on the regulation of the Yeast Metabolic Cycle: a multi-omic integrative approach

Abstract:

The Yeast Metabolic Cycle (YMC) is a model system in which levels of around 60% of the yeast transcripts cycle over time. The spatial and temporal resolution provided by the YMC has revealed that changes in the yeast metabolic landscape and chromatin status can be related to cycling gene expression. However, the interplay between histone modifications and transcription factor activity during the YMC is still poorly understood. Here we apply an innovative statistical approach to integrate chro...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.3389/fgene.2018.00578

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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Department of Biochemistry
Role:
Author
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Publisher:
Frontiers Media Publisher's website
Journal:
Frontiers in Genetics Journal website
Volume:
9
Article number:
578
Publication date:
2018-11-30
Acceptance date:
2018-11-08
DOI:
EISSN:
1664-8021
Pmid:
30555512
Source identifiers:
954495
Language:
English
Keywords:
Pubs id:
pubs:954495
UUID:
uuid:491accb8-d590-4572-8d56-fe4b23f3d866
Local pid:
pubs:954495
Deposit date:
2019-02-27

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