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Thesis

The critical role of IL-23 receptor positive T cells in the pathogenesis of anterior uveitis associated with spondyloarthropathy

Abstract:

The spondyloarthropathies (SpAs) are a group of chronic inflammatory diseases which predominantly affect the joints of the axial skeleton. However, many patients with SpA may have extra-articular manifestations within the skin and gut. Pathology of SpA in all of these tissues has been shown in recent studies to be driven by local resident populations of interleukin (IL)-23 responsive cells. The eye is also involved in these diseases, with uveitis occurring in up to 40% of patients with SpA...

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Division:
MSD
Department:
NDORMS
Sub department:
Botnar Research Centre
Oxford college:
Hertford College
Role:
Author

Contributors

Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Supervisor
Institution:
University of Oxford
Division:
MSD
Department:
NDORMS
Sub department:
Kennedy Institute for Rheumatology
Role:
Supervisor
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
University of Oxford
Language:
English
Keywords:
Subjects:
Deposit date:
2022-06-22

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