Journal article
Synonymous codon usage influences the local protein structure observed
- Abstract:
-
Translation of mRNA into protein is a unidirectional information flow process. Analysing the input (mRNA) and output (protein) of translation, we find that local protein structure information is encoded in the mRNA nucleotide sequence. The Coding Sequence and Structure (CSandS) database developed in this work provides a detailed mapping between over 4000 solved protein structures and their mRNA. CSandS facilitates a comprehensive analysis of codon usage over many organisms. In assigning trans...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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Authors
Funding
Bibliographic Details
- Publisher:
- Oxford University Press Publisher's website
- Journal:
- Nucleic Acids Research Journal website
- Volume:
- 38
- Issue:
- 19
- Pages:
- 6719-6728
- Publication date:
- 2010-01-01
- DOI:
- EISSN:
-
1362-4962
- ISSN:
-
0305-1048
Item Description
- Language:
- English
- Subjects:
- UUID:
-
uuid:49b17980-6e6e-4d15-a977-7bc78a063824
- Local pid:
- ora:6013
- Deposit date:
- 2012-01-12
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Terms of use
- Copyright holder:
- R Saunders & C M Deane
- Copyright date:
- 2010
- Notes:
- This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/2.5), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
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