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Effect of CFIm68 knockdown on RNA polymerase II transcription

Abstract:

Objectives

Transcription of eukaryotic protein-coding genes by RNA polymerase II (pol II) is highly regulated at initiation, elongation and termination. Transcription is also coordinated with co-transcriptional processing of the emerging pre-mRNA by capping, splicing, and cleavage and polyadenylation. Polyadenylation (poly(A)) site recognition, which defines the end of the mRNA, relies on the cleavage and polyadenylation (CPA) complex. It was previously observed tha...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1186/s13104-019-4582-8

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Pathology Dunn School
Role:
Author
ORCID:
0000-0002-4130-9050
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
Pathology Dunn School
Oxford college:
Oriel College
Role:
Author
ORCID:
0000-0001-5276-9645
Publisher:
BioMed Central Publisher's website
Journal:
BMC Research Notes Journal website
Volume:
12
Article number:
554
Publication date:
2019-09-02
Acceptance date:
2019-08-21
DOI:
EISSN:
1756-0500
Pmid:
31477156
Source identifiers:
1049341
Language:
English
Keywords:
Pubs id:
pubs:1049341
UUID:
uuid:4a15659c-ca4b-4e8b-b3ee-0d1d3a319968
Local pid:
pubs:1049341
Deposit date:
2019-10-23

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