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Journal article

Post‐translational control of transcription factors: methylation ranks highly

Abstract:

Methylation of lysine and arginine residues on histones has long been known to determine both chromatin structure and gene expression. In recent years, the methylation of non‐histone proteins has emerged as a prevalent modification which impacts on diverse processes such as cell cycle control, DNA repair, senescence, differentiation, apoptosis and tumourigenesis. Many of these non‐histone targets represent transcription factors, cell signalling molecules and tumour suppressor proteins. Eviden...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1111/febs.13524

Authors


More by this author
Institution:
University of Oxford
Department:
Oncology
Role:
Author
ORCID:
0000-0003-4327-0425
More by this author
Institution:
University of Oxford
Division:
MSD
Department:
Oncology
Oxford college:
Linacre College
Role:
Author
Publisher:
Wiley Publisher's website
Journal:
FEBS Journal Journal website
Volume:
282
Issue:
23
Pages:
4450-4465
Publication date:
2015-10-16
Acceptance date:
2015-09-21
DOI:
EISSN:
1742-4658
ISSN:
1742-464X
Pmid:
26402372
Source identifiers:
582941
Language:
English
Keywords:
Pubs id:
pubs:582941
UUID:
uuid:4a4b9183-fc28-48eb-bbc9-f103122b89b8
Local pid:
pubs:582941
Deposit date:
2018-07-05

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