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Thesis

Exploring the fold space preferences of ancient and newborn protein superfamilies

Abstract:

Protein evolution is a complex and diverse process, yielding an incredible assortment of biological functions and pathways occurring in the cells of living organisms. The way in which a protein's structure is constrained by its functional role and its notable conservation across even distant evolutionary relationships highlight structure as an important unit when considering the evolutionary dynamics of proteins. This thesis attempts to place the structural landscape of the protein univers...

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Institution:
University of Oxford
Research group:
Oxford Protein Informatics Group
Oxford college:
New College
Department:
Mathematical,Physical & Life Sciences Division - Statistics
Role:
Author

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Role:
Supervisor
Publication date:
2014
Type of award:
DPhil
Level of award:
Doctoral
Awarding institution:
Oxford University, UK
URN:
uuid:4a619051-db24-4a4c-bdad-61899bc1de03
Local pid:
ora:11812

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