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Journal article

Complete sequencing of plasmids containing blaOXA-163 and blaOXA-48 in Escherichia coli sequence type 131.

Abstract:

OXA-48-like enzymes have emerged as important extended-spectrum β-lactamases/carbapenemases in Escherichia coli sequence type 131 (ST131). We report the structures of the first fully sequenced blaOXA-163 plasmid and of two other blaOXA-48 plasmids in this lineage. blaOXA-163 was located on a 71-kb IncN plasmid with other resistance genes. blaOXA-48 was present on IncL/M plasmids, genetically similar to other blaOXA-48 plasmid sequences, and consistent with interspecies/interlineage spread. Th...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1128/aac.01130-16

Authors


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Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
Role:
Author
More by this author
Institution:
University of Oxford
Division:
Medical Sciences Division
Department:
NDM; NDM Experimental Medicine
Role:
Author
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Calgary Laboratory Services More from this funder
Public Health England More from this funder
Department of Health More from this funder
National Institute for Health Research More from this funder
Publisher:
American Association for Microbiology Publisher's website
Journal:
Antimicrobial Agents and Chemotherapy Journal website
Volume:
60
Issue:
11
Pages:
6948-6951
Publication date:
2016-09-01
Acceptance date:
2016-08-23
DOI:
ISSN:
1098-6596 and 0066-4804
Pmid:
27600043
Source identifiers:
645803
Language:
English
Keywords:
Pubs id:
pubs:645803
UUID:
uuid:4a86d203-16c1-48e1-91f0-f9bc229b5733
Local pid:
pubs:645803
Deposit date:
2017-11-14

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