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Parenteral exposure to high HIV viremia leads to virus-specific T cell priming without evidence of infection.

Abstract:

Previous studies on CTL responses in HIV-exposed uninfected individuals assumed that the patients were exposed to replicating HIV, but the possibility that the immune responses detected were primed by exposure to a defective virus or viral antigen could not be excluded. Epidemiological and laboratory analysis of a nosocomial outbreak of acute hepatitis B unequivocally allowed the identification of an HIV-1- and HBV-co-infected patient with high plasma levels of both viruses, as the source cas...

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Publication status:
Published

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Publisher copy:
10.1002/eji.200424889

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Journal:
European journal of immunology
Volume:
34
Issue:
11
Pages:
3208-3215
Publication date:
2004-11-01
DOI:
EISSN:
1521-4141
ISSN:
0014-2980
Source identifiers:
176603

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