Thesis
The role of antigen in the maintenance and localisation of CD8+ T-cells in the context of liver stage malaria
- Abstract:
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A highly effective vaccine against malaria is urgently needed, with leading vaccination strategies involving the induction of protective antigen-specific CD8+ T-cells via heterologous prime-boost viral vector immunization, targeting primarily the pre- erythrocytic liver stages of the Plasmodium falciparum lifecycle. To date, the greatest immunogenicity has been obtained through a heterologous prime boost regimen, where vaccination with an Adenoviral vector is followed 8 weeks la...
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Authors
Contributors
+ Spencer, A
Role:
Supervisor
+ Hill, A
Role:
Supervisor
+ Germain, R
Role:
Supervisor
Funding
Wellcome Trust-NIH Fellowship
More from this funder
Bibliographic Details
- Type of award:
- DPhil
- Level of award:
- Doctoral
- Awarding institution:
- University of Oxford
Item Description
- Language:
- English
- Keywords:
- Subjects:
- UUID:
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uuid:4b1ce436-316f-43da-bacf-3b1e178f2f40
- Deposit date:
- 2018-09-17
Related Items
Terms of use
- Copyright holder:
- Gola, A
- Copyright date:
- 2018
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