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Cerebrovascular risk factors impact frontoparietal network integrity and executive function in healthy ageing

Abstract:

Healthy cognitive ageing is a societal and public health priority. Cerebrovascular risk factors increase the likelihood of dementia in older people but their impact on cognitive ageing in younger, healthy brains is less clear. The UK Biobank provides cognition and brain imaging measures in the largest population cohort studied to date. Here we show that cognitive abilities of healthy individuals (N = 22,059) in this sample are detrimentally affected by cerebrovascular risk facto...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1038/s41467-020-18201-5

Authors


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Institution:
University of Oxford
Division:
MSD
Department:
Experimental Psychology
Role:
Author
ORCID:
0000-0003-2192-378X
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Institution:
University of Oxford
Division:
MSD
Department:
Nuffield Department of Population Health
Role:
Author
ORCID:
0000-0002-4516-5103
More by this author
Role:
Author
ORCID:
0000-0001-8166-069X
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Department of Health More from this funder
Publisher:
Nature Research Publisher's website
Journal:
Nature Communications Journal website
Volume:
11
Article number:
4340
Place of publication:
England
Publication date:
2020-09-07
Acceptance date:
2020-08-12
DOI:
EISSN:
2041-1723
Pmid:
32895386

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