Journal article
Chronic activation of γ2 AMPK induces obesity and reduces β cell function
- Abstract:
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Despite significant advances in our understanding of the biology determining systemic energy homeostasis, the treatment of obesity remains a medical challenge. Activation of AMP-activated protein kinase (AMPK) has been proposed as an attractive strategy for the treatment of obesity and its complications. AMPK is a conserved, ubiquitously expressed, heterotrimeric serine/threonine kinase whose short-term activation has multiple beneficial metabolic effects. Whether these translate into long-te...
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- Publication status:
- Published
- Peer review status:
- Peer reviewed
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(Version of record, pdf, 4.9MB)
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- Publisher copy:
- 10.1016/j.cmet.2016.04.003
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Authors
Funding
+ National Institute for Health Research
More from this funder
Funding agency for:
Yavari, A
Grant:
Research Training Fellowship (086632/Z/08/Z
+ BHF Centre of Research Excellence
More from this funder
Funding agency for:
Yavari, A
Grant:
Research Training Fellowship (086632/Z/08/Z
+ Wellcome Trust
More from this funder
Funding agency for:
Yavari, A
Grant:
Research Training Fellowship (086632/Z/08/Z
+ BHF Centre of Research Excellence
More from this funder
Funding agency for:
Watkins, H
Grant:
MR/K019023/1
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Bibliographic Details
- Publisher:
- Cell Press Publisher's website
- Journal:
- Cell Metabolism Journal website
- Publication date:
- 2016-04-28
- Acceptance date:
- 2016-04-01
- DOI:
- EISSN:
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1932-7420
- ISSN:
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1550-4131
- Source identifiers:
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616409
Item Description
- Pubs id:
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pubs:616409
- UUID:
-
uuid:4c6a4682-da59-4812-89f8-36449b4fb3d5
- Local pid:
- pubs:616409
- Deposit date:
- 2016-04-19
Terms of use
- Copyright holder:
- Yavari et al
- Copyright date:
- 2016
- Notes:
- © 2016 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license.
- Licence:
- CC Attribution (CC BY)
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