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Journal article

Targeted RNA sequencing enhances gene expression profiling of ultra-low input samples

Abstract:

RNA-seq is the standard method for profiling gene expression in many biological systems. Due to the wide dynamic range and complex nature of the transcriptome, RNA-seq provides an incomplete characterization, especially of lowly expressed genes and transcripts. Targeted RNA sequencing (RNA CaptureSeq) focuses sequencing on genes of interest, providing exquisite sensitivity for transcript detection and quantification. However, uses of CaptureSeq have focused on bulk samples and its performance...

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Publication status:
Published
Peer review status:
Peer reviewed

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Publisher copy:
10.1080/15476286.2020.1777768

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Publisher:
Taylor & Francis Publisher's website
Journal:
RNA Biology Journal website
Volume:
17
Issue:
12
Pages:
1741-1753
Publication date:
2020-06-28
Acceptance date:
2020-04-20
DOI:
EISSN:
1555-8584
ISSN:
1547-6286
Language:
English
Keywords:
Pubs id:
1112902
Local pid:
pubs:1112902
Deposit date:
2020-06-18

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